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Streptomyces spp. on various cultivation media. Production of different pigments and formation of aerial mycelia. Colonies after approximately 15 days of cultivation in aerobic
atmosphere, 28°C.
Streptomycetes are characterised by a complex secondary metabolism. They produce over two-thirds of the clinically useful antibiotics of natural origin. The now uncommonly-used streptomycin
(the first antibiotic effective against tuberculosis; S.A.Waksman,1952, The Nobel Prize in Physiology/Medicine) takes its name directly from Streptomyces.
Members of the Streptomyces genus are the source for innumerable other antibacterial pharmaceutical agents; among the most important of these are:
| Cefoxitin |
S. lactamdurans |
Neomycin |
S. fradiae |
| Chloramphenicol |
S. venezuelae |
Puromycin |
S. alboniger |
| Daptomycin |
S. roseosporus |
Rifamycin |
S. mediterranei |
| Fosfomycin |
S. fradiae |
Tetracycline |
S. rimosus |
| Lincomycin |
S. lincolnensis |
Vancomycin |
S. orientalis |
Thanks to clavulanic acid (from S. clavuligerus) are
antibiotics like amoxicillin (amoxicillin/clavulanate=Augmentin) or ticarcillin (ticarcillin/ clavulanate=Timentin) still very useful in treatment of many bacterial infections.
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